Renal Biopsy Cases

 Introduction

In renal biopsy, a small sample of kidney tissue is removed with a needle. This test is typically conducted in order to evaluate a transplanted kidney. It is also used to account for an unexplained decrease in kidney function, persistent blood in the urine, or protein in the urine. In addition, a kidney biopsy may also be used to determine the severity of kidney disease or to find out if a particular treatment for a kidney disease is effective. Patients suffering from nephrotic syndrome (a disorder in which kidneys leak large amounts of urine), acute nephritic syndrome (a disorder characterized by large pores permitting passage of protein and red blood cells into the urine) and renal failure (a condition in which the kidneys fail to filter toxins and other waste products from the blood) are also recommended to undergo a renal biopsy.

Healthy and functioning kidneys clean the blood by filtering and removing excess fluid, minerals and wastes. In addition, kidneys produce hormones that keep the bones strong and blood healthy. However, if the kidneys are damaged, individuals may experience a buildup of harmful wastes in the body. Other symptoms such as an increased blood pressure, fluid retention, and lack of red blood cells are all signs of kidney failure. In many cases, a renal biopsy can provide a chance for doctors and medical professionals to determine the extent of the failure and to recommend a course of action or treatment.

There are three types of renal biopsies: ultrasound-guided kidney biopsy, CT-guided kidney biopsy, and surgical biopsy. The most common kidney biopsy uses ultrasound to guide the doctor to the proper area of the kidney.

In general, renal biopsy is a safe and effective procedure. However, there are possible risks. Blood in the urine is the most common complication after a biopsy is performed. This type of bleeding typically stops within a few days. Several patients experience temporary pain lasting a few hours at the biopsy site immediately after the biopsy is completed. Other patients have experienced  an arteriovenous fistula which occurs when the biopsy needle accidentally damages the walls of a nearby artery and vein and creates an abnormal connection. This type of fistula usually causes no symptoms and closes on its own. In rare cases, a collection of blood around the kidney becomes infected, but can be easily treated with proper antibiotics and surgical drainage.


Case Studies

An Analysis of 2361 Cases of Renal Biopsy in Korea

Clinical Trials.gov

Crystal Induced Kidney Disease in Two Kidney Transplant Recipients

Clinical Research Studies

Nephrology, Dialysis, and Transplantation Case Studies

Outcome Study of Renal Biopsy Patients in Okinawa, Japan

Pattern of Morphology in Renal Biopsies of Nephrotic Syndrome Patients

Pseudoleukocytosis Secondary to Hepatitis C-associated Cryoglobulinemi

Renal Biopsy in the Very Elderly

Renal Biopsy in Acute Kidney Injuries: Who are We Missing?

Role of Electron Microscopy in Evaluation of Native Kidney Biopsy

The Report of 59 Patients with Renal Amyloidosis


General Educational Resources

Directory of Kidney and Urologic Diseases Organizations

NIDDK Image Library

National Kidney and Urologic Diseases Information Clearinghouse: Kidney and Urologic Diseases

National Kidney Disease Education Program


Publications

American Journal of Kidney Diseases

Frequency of Renal Diseases and Clinical Cases in Children

Safety and Adequacy in Percutaneous Biopsies in Pediatric Orthotopic Kidney Transplantation

Special Stains in Native and Transplant Kidney Biopsy Interpretation

Urologic Diseases in America

Renal and Urology News

Renal Business Today

Nephrology News and Issues

Kidney Times


Data and Statistics

Kidney and Urologic Disease Statistics for the United States

United Network for Organ Sharing

United States Renal Data System

Glossary of Clinical Trials Terms


Organizations

American Association of Kidney Patients

American Kidney Fund

National Kidney Foundation

National Library of Medicine

National Institutes of Health

Nephcure Foundation

Polycistic Kidney Research Foundation

National Kidney Cancer Association

The Nephron Information Center